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. 2014 Apr 22;9(4):e96091. doi: 10.1371/journal.pone.0096091

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© 2014 Lin et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Pulmonary resistance in animals of the sham (n = 7), vehicle (n = 9), and 10 mg/kg sesamin groups (n = 9) showed dose-dependent AHR in response to 3.125, 6.25, 12.5, and 25.0 mg/ml methacholine. Data were presented as mean± S.E.M. Statistical significance was defined as ^# p<0.05 and ^## p<0.01 for the OVA+vehicle group compared with the sham group; * p<0.05 for the sesamin group compared with the OVA+vehicle group.