Table 1.
Clinicopathologic features of triple negative breast cancers
| Variable | n = 205 |
|---|---|
|
Age at dignosis |
|
| Mean ± SD (years) |
48.4 ± 12.3 |
|
Age specific groups, N (%) |
|
| < 30 years |
15 (7.3%) |
| 31-40 years |
47 (22.9%) |
| 41-50 years |
61 (29.8%) |
| 51-70 years |
70 (34.1%) |
| > 70 years |
12 (5.9%) |
|
Tumor size |
|
| Mean ± SD (mm) |
38.2 ± 16.2 |
|
Size specific groups, n (%) |
|
| ≤ 2.0 cm (pT1) |
14 (12.7%) |
| 2.0-5.0 cm (pT2) |
81 (73.6%) |
| > 5.0 cm (pT3) |
15 (13.6%) |
| Without surgery/trucut biopsy$ |
95 |
|
Histological type, n (%) |
|
| Infiltrating ductal carcinoma (NOS) |
158 (77.1%) |
| Infiltrating lobular carcinoma |
05 (2.4%) |
| Metaplastic carcinoma |
22 (10.7%) |
| Invasive papillary carcinoma |
07 (3.4%) |
| Infiltrating carcinoma with medullary features |
12 (5.9%) |
| Missed ductal and lobular carcinoma |
01 (0.5%) |
|
Histologic grade, n (%) |
|
| Grade I (well differentiated) |
|
| Grade II (moderately differentiated) |
|
| Grade III (poorly differentiated) |
10 (4.9%) |
| 65 (31.7%) | |
| 130 (63.4%) | |
|
Lymphovascular invasion, n (%) |
|
| Present |
|
| Not present |
|
| Cannot be assessed$ |
30 (27.3%) |
| 80 (72.7%) | |
| 95 | |
|
Necrosis, n (%) |
|
| Geographic necrosis involving > 40% of tumor |
|
| Necrosis involving < 40% of tumor |
|
| Necrosis is absent |
34 (30.9%) |
| Cannot be completely assessed$ |
72 (65.5%) |
| 04 (3.6%) | |
| 95 | |
|
Lymphocytic infiltration, n (%) |
|
| Extensive lymphocytic infiltration |
21 (19.1%) |
| Mild to moderate lymphocytic infiltration |
89 (80.9%) |
| Cannot be completely assessed$ |
95 |
|
Lymph node status, n (%) |
|
| Negative lymph nodes (N0) |
57 (51.8%) |
| 1-3 positive lymph nodes (N1) |
24 (21.8%) |
| 4-9 positive lymph nodes (N2) |
11 (10.0%) |
| ≥ 10 positive lymph nodes (N3) |
18 (16.4%) |
| Lymph nodes dissection not done |
95 |
|
Extranodal extension, n (%) |
|
| Present |
|
| Not present |
15 (13.6%) |
| Lymph nodes dissection not done |
95 (86.4%) |
| 95 | |
|
Ki-67 proliferation index |
|
| Mean ± SD (%) |
45.2 ± 25.2 |
|
Ki-67 proliferation index, (categories), n (%) |
|
| ≤ 15% (low) |
|
| 16-30% (Intermediate) |
|
| >30% (High) |
32 (15.6%) |
| 37 (18.0%) | |
| 136 (66.3%) | |
|
Type of surgery n (%) |
|
| Modified radical mastectomy |
|
| Breast conservation surgery |
|
| Surgery not done/trucut biopsy |
90 (43.9%) |
| 15 (7.3%) | |
| 95 (46.3%) | |
|
Laterality n (%) |
|
| Right |
94 (45.9%) |
| Left | 111 (54.1%) |
$Cases are of trucut biopsies without surgery.