Table 5.

Genes with significant expression in high responders^* (n=10) vs. low responders** (n=9)

After marathon training - Decreased gene expression
Transcript id	Gene	Fold change (FC)
7969794	LOC100132099	−1.58
8049530	LRRFIP1	−1.58
7919269	RNU1-1	−1.89
7919349	RNU1-1	−1.89
7898375	RNU1-1	−1.86
7898411	RNU1-1	−1.86
7912800	RNU1-1	−1.86
7912850	RNU1-1	−1.86
7919576	RNU1-1	−1.86
7973896	RNU1-1	−1.85
7978568	RNU1-1	−1.85
7897801	RNU5E	−1.89
7920873	SNORA42	−3.49
8117018	---	−1.86
7932635	---	−1.63
7965150	---	−1.62
After marathon training - increased gene expression
Transcript id	Gene	Fold change (FC)
8005225	LOC162632	2.35

No genes met FDR significance criteria for differential mRNA expression in blood collected at baseline.

*High Responders are defined as those individuals who fell in the upper quartile (upper 25%) of percent change in rVO₂ max.

**Low Responders are defined as those individuals who fell below the upper quartile of percent change in rVO₂ max.