Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Feb 7;2:16. doi: 10.1186/2051-5960-2-16

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2014 Sokolowski et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Generation of caspase-dependent cleaved actin and tubulin neoepitopes in degenerating axons is BAX-dependent. The amount of CC3, fractin and TubulinΔCsp6 staining was quantified 6 hours after injury via Cell profiler. Data was normalized to the value calculated from the wild type ethanol-treated tissue in order to represent relative levels in each genotype and treatment. BAX deficient mice showed nearly complete loss of ethanol-induced generation of fractin and cleaved tubulin immunoreactivity.