Table 2.
Anthropometric and biochemical characteristics in T2DM patients stratified for the A/A and A/G TLR4 genotypes.
| A/A TLR4 positive individuals (n = 336) |
A/G TLR4 positive individuals (n = 31) |
P | |
|---|---|---|---|
| Age (years) | 66.01 (8.01) | 65.93 (7.18) | 0.958 |
| Male(∗) | 55.7 (187) | 67.7 (21) | 0.195 |
| BMI (kg/m2) | 28.59 (4.44) | 29.96 (4.38) | 0.102 |
| Total cholesterol (mg/dL) | 207.48 (37.27) | 193.94 (33.70) | 0.052 |
| HDL-cholesterol (mg/dL) | 52.35 (14.51) | 53.13 (16.83) | 0.778 |
| Triglycerides (mg/dL) | 133.78 (95.54) | 132.45 (89.52) | 0.822 |
| Fasting glucose (mg/dL) | 161.45 (45.95) | 163.13 (47.28) | 0.846 |
| HbA1C (%) | 7.40 (1.18) | 7.38 (1.41) | 0.940 |
| Fasting insuline (uiU/mL) | 6.91 (5.73) | 6.17 (3.73) | 0.550 |
| WBC (103/L) | 6.70 (1.65) | 6.77 (1.67) | 0.826 |
| High-sensitivity C-reactive protein (mg/dL) | 4.20 (5.74) | 3.97 (4.04) | 0.971 |
| Fibrinogen (mg/dL) | 302.02 (78.95) | 324.06 (77.87) | 0.117 |
| Creatinine (mg/dL) | 0.92 (0.31) | 0.90 (0.25) | 0.726 |
| HOMA-IR (mg/dL ∗ uiU/mL) | 2.81 (2.71) | 2.47 (1.43) | 0.499 |
| Urea (mg/dL) | 40.91 (12.67) | 38.42 (8.69) | 0.284 |
| LDL cholesterol (mg/dL) | 117.54 (30.43) | 106.05 (28.74) | 0.044 |
| Apo-A1 (mg/dL) | 165.90 (35.26) | 157.81 (34.36) | 0.221 |
| Apo-B (mg/dL) | 102.54 (25.87) | 97.68 (27.05) | 0.319 |
Variables are expressed as mean (Standard Deviation).
(∗)Categorical variable expressed as percentage (n).