Table 2.
Mean values derived from the optic nerve head ophthalmoscopic examination, disc damage likelihood scale, and optical coherence tomography according to diagnosis.
| Normal | Glaucoma suspect | Glaucoma | P value* | Post hoc analysis | |||
|---|---|---|---|---|---|---|---|
| Normal versus Glaucoma suspect | Normal versus Glaucoma | Glaucoma suspect versus Glaucoma | |||||
| DDLS evaluated using 3D optic disc photography | 0.58 ± 0.50 | 2.03 ± 0.66 | 4.23 ± 1.23 | <0.001 | <0.01 | <0.001 | <0.001 |
| Ophthalmoscopic examination. | |||||||
| Horizontal C/D ratio | 0.37 ± 0.10 | 0.61 ± 0.11 | 0.63 ± 0.18 | <0.001 | <0.001 | <0.001 | 0.673 |
| Vertical C/D ratio | 0.38 ± 0.09 | 0.57 ± 0.13 | 0.59 ± 0.20 | <0.001 | <0.001 | <0.001 | 0.590 |
| 3D optic disc photography | |||||||
| Vertical C/D ratio | 0.48 ± 0.11 | 0.57 ± 0.03 | 0.64 ± 0.11 | <0.001 | <0.001 | <0.001 | <0.001 |
| Superior rim width | 0.45 ± 0.10 | 0.41 ± 0.08 | 0.32 ± 0.09 | <0.001 | 0.182 | <0.001 | <0.001 |
| Inferior rim width | 0.47 ± 0.12 | 0.44 ± 0.10 | 0.36 ± 0.13 | <0.001 | 0.361 | <0.001 | 0.001 |
| Cup area | 0.68 ± 0.35 | 1.04 ± 0.20 | 1.38 ± 0.74 | <0.001 | <0.001 | <0.001 | 0.005 |
| Disc area | 2.55 ± 0.55 | 3.17 ± 0.24 | 3.10 ± 0.89 | <0.001 | <0.001 | 0.002 | 0.657 |
| Rim area | 1.87 ± 0.35 | 2.09 ± 0.20 | 1.71 ± 0.41 | <0.001 | 0.014 | 0.089 | <0.001 |
| C/D area ratio | 0.25 ± 0.10 | 0.33 ± 0.65 | 0.42 ± 0.12 | <0.001 | 0.002 | <0.001 | <0.001 |
| Rim disc area ratio | 0.74 ± 0.10 | 0.66 ± 0.06 | 0.57 ± 0.12 | <0.001 | 0.002 | <0.001 | <0.001 |
| Cup volume | 0.11 ± 0.07 | 0.31 ± 0.17 | 0.37 ± 0.34 | <0.001 | <0.001 | <0.001 | 0.285 |
| Disc volume | 0.76 ± 0.33 | 1.49 ± 0.32 | 1.39 ± 1.01 | <0.001 | <0.001 | 0.005 | 0.352 |
| Rim volume | 0.35 ± 0.17 | 0.64 ± 0.33 | 0.32 ± 0.23 | <0.001 | <0.001 | 0.669 | 0.001 |
| Mean cup depth | 0.18 ± 0.13 | 0.31 ± 0.15 | 0.36 ± 0.34 | <0.001 | 0.001 | 0.005 | 0.486 |
| Maximum cup depth | 0.51 ± 0.29 | 1.43 ± 1.61 | 1.10 ± 1.39 | 0.019 | 0.010 | 0.018 | 0.326 |
| Height variation contour | 0.81 ± 0.71 | 1.25 ± 1.34 | 1.25 ± 1.35 | 0.234 | 0.281 | 0.101 | 0.994 |
| Cirrus OCT RNFL and optic nerve head analysis | |||||||
| Rim area | 1.20 ± 0.28 | 1.14 ± 0.22 | 0.868 ± 0.33 | <0.001 | 0.136 | <0.001 | <0.001 |
| Disc area | 1.92 ± 0.40 | 2.51 ± 0.42 | 2.26 ± 0.56 | <0.001 | <0.001 | 0.008 | 0.009 |
| Average C/D ratio | 0.54 ± 0.14 | 0.71 ± 0.06 | 0.74 ± 0.14 | <0.001 | <0.001 | <0.001 | 0.277 |
| Vertical C/D ratio | 0.50 ± 0.13 | 0.68 ± 0.05 | 0.72 ± 0.14 | <0.001 | <0.001 | <0.001 | 0.050 |
| Cup volume | 0.20 ± 0.12 | 0.53 ± 0.23 | 0.55 ± 0.34 | <0.001 | <0.001 | <0.001 | 0.646 |
| Average RNFL thickness | 95.33 ± 8.61 | 91.60 ± 9.56 | 76.48 ± 16.30 | <0.001 | 0.167 | <0.001 | <0.001 |
*Statistical significance was tested by ANOVA.
OCT: optical coherence tomography.
C/D ratio: cup/disc ratio.
RNFL: retinal nerve fiber layer.