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. 2014 Apr 19;88(5):1161–1183. doi: 10.1007/s00204-014-1243-5

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© The Author(s) 2014

Open AccessThis article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.

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Fig. 3 — a Cell shape approximation of one hepatocyte (yellow) in relation to bile canaliculi (green) and sinusoids (red). Such reconstructions can be obtained for individual cells from the larger tissue blocks shown in Fig. 2a. The scale bar is 30 μm. b Individual slice level of a z-stack showing a bile duct and a canal of Hering in the upper right corner. The scale bar is 50 μm. c Reconstructions from the z-stacks level on the DPPIV/CD26 signal. The upper panel shows the reconstructed raw data, whereas the bile duct (yellow) and Hering canal (white) are highlighted in the lower panel. The scale bars are 30 μm. BC bile canaliculi, BD bile duct, HC Hering canal, PV portal vein (colour figure online)