Table 2.

Results of cluster analysis of 1429 transcripts by DAVID.

Cluster	Gene ontology terms and annotations	Count*	Enrichment score**	P value	FDR***
Processes related to functioning of immune system
Immune system process	GO:0002376	100	6.21	1.8E − 7	5.4E − 4
Defense response	GO:0006952	68	3.72	8.0E − 7	6.2E − 4
Response to cytokine stimulus	GO:0034097	17	2.92	1.2E − 5	5.5E − 3
Positive regulation of I-kappaB kinase/NF-kappaB signaling	GO:0043123	19	2.82	1.3E − 5	5.1E − 3
Processes related to cellular transport
Endosome	GO:0005768	41	4.12	2.8E − 6	3.6E − 4
Vesicle-mediated transport	GO:0016192	63	3.52	3.1E − 6	2.0E − 3
Protein kinase cascade (intracellular signal transduction)	GO:0035556	48	3.04	5.6E − 7	8.8E − 4
Membrane-enclosed lumen	GO:0031974	141	2.3	6.4E − 4	2.0E − 2
Intracellular transport	GO:0046907	66	1.55	2.9E − 5	8.1E − 3
Endoplasmic reticulum lumen	GO:0005788	14	1.50	6.7E − 4	1.9E − 2
Other processes
Alternative splicing	GO:0008380	514	9.31	1.9E − 10	5.0E − 8
Lysosome	GO:0005764	21	2.64	2.1E − 4	1.4E − 2
Regulation of catalytic activity	GO:0050790	77	2.23	1.5E − 4	2.9E − 2
Regulation of molecular function	GO:0065009	85	2.23	2.3E − 4	3.9E − 2
Regulation of catalytic activity	GO:0050790	77	1.49	1.5E − 4	2.9E − 2

*Count is number of genes in a cluster.

**Enrichment score ranks the biological significance of gene groups based on overall EASE scores of all enriched annotation terms.

***False-discovery rate (FDR) or the correction of values using the Benjamini-Hochberg method.