Skip to main content
. 2014 Jan 21;5(3):659–666. doi: 10.18632/oncotarget.1597

Table 2. Top individual targets enriched among molecules producing a cytotoxic effect in the IGROV1 Ovarian cell line.

P-value FDR corrected Target (Gene Symbol) Odds Ratio The number of active compounds known to target gene The total number of active compounds (IC50 < 10−6) The number of inactive compounds known to target gene The total number of inactive compounds (IC50 >10−6)
1.82E-42 NCOA3 22.2 68 231  37 2004
2.32E-42 NR5A1 18.1 73 231  50 2004
7.76E-42 NR5A2 17.3 73 231  52 2004
9.26E-38 NCOA1 7.3 57 231  26 2004
3.07E-36 IDH1 24.9 88 231 123 2004
8.29E-34 CFTR 9.4 86 231 128 2004
1.57E-33 PAX8 8.7 71 231  76 2004
1.09E-28 MITF 11.3 81 231 137 2004
2.49E-28 NFE2L2 7.4 77 231 123 2004