Table 5. Statistics for MITF-related poly-pharmacological patterns in HCT116 cells with a targeted deletion of the PTEN gene.

P-value FDR corrected	Target/pattern (Gene Symbol)	Odds Ratio	The number of active compounds known to target gene/pattern	The total number of active compounds (IC50 < 10−6)	The number of inactive compounds known to target gene/pattern	The total number of inactive compounds (IC50 >10−6)
< 1.00e-286	MITF	78.6	456	1621	510	102910
< 1.00e-286	ATNX2	74.2	421	1621	484	102910
< 1.00e-286	SMAD3	24.5	328	1621	1053	102910
6.55e-279	MITF and SMAD3	188.5	189	1621	72	102910
< 1.00e-300	MITF and ATXN2	240.1	247	1621	77	102910
< 1.00e-230	MITF and ATXN2 and SMAD3	500.2	117	1621	16	102910