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. 2014 Feb 2;5(3):754–763. doi: 10.18632/oncotarget.1768

Figure 6. MUC1 is involved in increase of ADAM10 and ADAM17 expression.

Figure 6

Western blot performed on cell extracts obtained from EV- and MUC1FL-ACHN clones treated or not by 5 μM of CP-2 and GO-203 peptides (A), scramble, sh1.1 and sh1.2 786-O clones (B) or primary proximal tubular epithelial cells (PTE), RCC4, RCC10 and 786-O cancer cell lines (C). The density of each marker was measured and ADAM10/actin and ADAM17/actin ratios were determined and represented as histograms. Expression in control cells was arbitrarily set to 1.