Table 1.

Effects of diazepam (DZP) on up state duration and on the number of action potentials (AP) per up state in organotypic slice cultures from the neocortex of wild type mice. Data are normalized to control condition.

DZP in μM	up state duration	AP per up state
6.25	0.94 ± 0.12 (n = 19)	0.80 ± 0.14 (n = 18)
12.5	1.30 ± 0.17 (n = 28)	1.41 ± 0.18 (n = 29)
25	1.35 ± 0.15 (n = 33)	1.29 ± 0.14 (n = 34)
50	1.29 ± 0.12 (n = 34)	0.97 ± 0.10 (n = 35)

Diazepam induced changes are not significantly different from control condition (t-test, P > 0.05).