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. Author manuscript; available in PMC: 2014 Apr 23.
Published in final edited form as: Eur J Neurosci. 2011 Jul 4;34(3):362–373. doi: 10.1111/j.1460-9568.2011.07782.x

Table 1.

Morphological properties of newborn neurons in WT and mutant mice

Area under the curve Number of nodes Total dendritic length

DPI Genotype n (μm2) F P F P (μm) F P
14 WT (control) 29 3531 ± 178 F2.90 = 2.7 0.041 5.6 ± 0.3 F2.90 = 7.7 0.0001 302.2 ± 16.3 F2.90 = 2.9 0.039
α2-KO 24 3522 ± 187 N.S 5.7 ±0.3 N.S 289.9 ± 19.9 NS
α4-KO 21 3021 ± 187 0.028 3.9 ± 0.25 0.0002 237.4 ± 18.7 0.01
δ-KO 20 3715 ± 200 N.S 5.85 ± 0.25 N.S 314.4 ± 21.3 NS
28 WT (control) 22 6368 ± 251 F2.77 = 4.8 0.004 5.4 ± 0.21 F2.77 = 9.68 0.001 689.2 ± 35.1 F2.77 = 1.1 < 0.0001
α2-KO 26 5519 ± 250 0.02 4.46 ± 0.21 0.006 581 ± 32.5 0.03
α4-KO 19 4964 ± 318 0.04 4.05 ± 0.3 0.0004 468.6 ± 41.6 < 0.0001
δ-KO 14 6814 ± 242 N.S 5.9 ± 0.33 N.S 778.3 ± 40.2 N.S
42 WT (control) 23 5921 ± 216 F2.52 = 9.79 0.002 5.9 ± 0.28 F2.52 = 13.3 < 0.001 639.4 ± 25.9 F2.52 = 13.1 < 0.001
α2-KO 36 4709 ± 218 0.0002 4.2 ± 0.23 < 0.0001 465.5 ± 33.4 0.0001
α4-KO 27 4612 ± 191 0.0002 4.18 ± 0.24 < 0.0001 413.3 ± 28.8 < 0.0001

n, number of GFP+ cells. Values are given as mean ± SEM, with the corresponding P value of post hoc analysis. For each time-point and genotype, the cells analyzed were derived from four or five mice successfully injected with eGFP retroviruses. ‘Area under the curve’ represents the distribution of the number of intersections with concentric circles as a function of distance from the soma (see Fig. 3). Statistical comparisons are between genotypes at defined time-points.