Fig. 3.
Neonatal ethanol treatment does not alter DAT function in striatum of preadolescent rats. Rat pups were injected (sc) with lobeline (3 mg/kg) or saline (controls), and striatum was obtained 20 min later. Kinetic analysis of synaptosomal [3H]DA uptake was determined in the presence of GBR 12909 (10 μM). Vmax (picomoles per milligram per minute), and Km (nM) are expressed as mean±SEM n=10–14 for each treatment group. The control group is composed of the pooled data from subjects from non-treated and intubated control groups. Data are collapsed across sex.