Table 1.

Relationships between IGF-1, GDS, and AVLT Domains (n = 94)

	Model a		Model b		Model c
	B (SE)	q value (p value)	B (SE)	q value (p value)	B (SE)	q value (p value)
Total learning
GDS‡	−1.62 (1.00)	.44 (.11)	−1.60 (1.00)	.44 (.11)	0.23 (1.41)	.87 (.87)
IGF-1 †			0.87 (1.62)	.79 (.59)	4.34 (2.49)	.16 (.082)
IGF-1† × GDS‡					−3.23 (1.79)	.071 (.071)
Immediate recall
GDS‡	−0.09 (0.34)	.80 (.80)	−0.09 (0.34)	.79 (.79)	0.57 (0.48)	.32 (.24)
IGF-1 †			−0.07 (0.55)	.90 (.90)	1.18 (0.85)	.16 (.16)
IGF-1† × GDS‡					−1.16 (0.61)	.071 (056)
Delayed recall
GDS‡	−0.34 (0.36)	.80 (.71)	−0.35 (0.36)	.60 (.33)	0.79 (0.49)	.24 (.11)
IGF-1 †			−0.57 (0.58)	.66 (.33)	1.58 (0.87)	.16 (.068)
IGF-1† × GDS‡					−2.01 (0.62)	.004 (.001)
Recognition
GDS‡	−0.36 (0.51)	.80 (.48)	−0.38 (0.51)	.60 (.45)	1.09 (0.70)	.24 (.12)
IGF-1 †			−1.00 (0.82)	.66 (.23)	1.79 (1.23)	.16 (.15)
IGF-1† × GDS‡					−2.60 (0.88)	.006 (.003)

Note. Confounding factors included age, gender, education, use of ERT, use of antihypertensive, and sleep quality.

^†IGF-1 high level was taken as referent.

^‡GDS was recoded as ln(GDS raw score +1).