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. 2014 Apr 3;2014:670743. doi: 10.1155/2014/670743

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Copyright © 2014 Jin Yu et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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The genes expression of ovarian tissues analyzed by Real-Time PCR. As is shown above, there were no obvious differences between 3β-hsd mRNA and gdf-9 mRNA among the three groups. The expression of cyp17 mRNA (9.35 ± 2.23), cyp19 mRNA (1.81 ± 0.22), ar mRNA (5.33 ± 1.24), and igf-1 mRNA (1.37 ± 0.25) in Model group was increased significantly than in the Control group (1.00 ± 0.00). After drug intervention, the expression of cyp17 mRNA (4.36 ± 0.39) and ar mRNA (3.45 ± 0.34) was statistically decreased, while cyp19 mRNA and igf-1 mRNA had no statistical differences (cyp19 mRNA: 1.93 ± 0.28; igf-1 mRNA: 1.21 ± 0.20). Model group (n = 6) versus Control group (n = 6): *P < 0.05; Drug group (n = 6) versus Model group (n = 6): ^Δ P < 0.05.