FIG. 1.

Assessment of the magnitude of spinal cord injuries. Open circles represent individual data points; closed circles represent group averages with standard error of the mean. (A) Cord volume loss, expressed as total cord volume relative to sham-operated controls. Note that cord total volume loss gradually increased with increasing injury severity (125 kDyn/mild, 175 kDyn/moderate, 200 kDyn/severe, and 225 kDyn/very severe; n=5, 7, 8, 6, and 5 from sham to very severe injury groups, respectively). *p<0.05, compared to sham-treated control spinal cords; ^♦p<0.05, compared to mild injury; ^Δp<0.05, compared to moderate injury. (B) Representative images of cord injury epicenters stained with eriochrome cyanin 4 weeks after injury (scale bar, 500 μm). (C) White matter loss at epicenter of injury, measured as the amount of myelin staining at the injury epicenter. *p<0.05, compared to sham; ^♦p<0.05, compared to mild injury. Color image is available online at www.liebertpub.com/neu