Table 1.
Genotype frequencies of the single nucleotide polymorphism SNP rs6886.
| SNP type |
CTRL | OC | FTC | BC | HapMap | ||||
|---|---|---|---|---|---|---|---|---|---|
| n= | % | n= | % | n= | % | n= | % | % | |
| homozygous-His (A/A) | 11 | 10.28 | 42 | 15.96 | 6 | 50.00 | 7 | 6.14 | 8 |
| homozygous-Arg (G/G) | 51 | 47.66 | 107 | 40.68 | 5 | 41.66 | 55 | 48.24 | 43 |
| heterozygous (G/A) | 45 | 42.05 | 114 | 43.34 | 1 | 8.33 | 52 | 45.61 | 48 |
| Total | 107 | 100 | 263 | 100 | 12 | 100 | 114 | 100 | 100 |
SNP rs6886 (c.1004A>G, p.His335Arg) genotype frequencies were determined in healthy controls (CTRL), ovarian carcinoma (OC), fallopian tube carcinoma (FTC), and breast cancer (BC) cases compared to the published data of the International HapMap Project (http://www.hapmap.org/). CapG reference sequence (NM_001747.3) was obtained from the RefSeq database (http://www.ncbi.nlm.nih.gov/refseq/).