FIG. 2.

Glial scar evolution and axon remodeling 1 week post-injury, with or without chondroitinase ABC (ChABC) treatment; double immunofluorescence labeling for glial fibrillary acidic protein (GFAP) (A,B, E, F; green on merge image), and phosphorylated microtubule associated protein 1B (MAP1B-P) (C, D, E, F; red on merge image) on spinal cord sections of untreated (Lesion) and ChABC-treated (Les+ChABC) animals. E and F are higher magnification merge images of insets in A,C and B,D, respectively. GFAP labeling is less intense after the treatment (compare A and B), and astrocytic extensions are longer and more often oriented toward the injury site. Bar: A–D, 130 μm; E-F, 15 μm. Color image is available online at www.liebertpub.com/neu