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Volcano plots of the significant gene expression changes in Tg4–42 and 5XFAD mice. Fold changes in gene expression of (A) young 5XFAD, (B) aged 5XFAD, and (C) aged Tg4–42 mice. Each dot represents one gene. Dashed lines illustrate statistical significance (p = 0.05). Red, down-regulated; green, up-regulated.
