FIG. 5.

Microtubule-associated protein (MAP)-2 expression in hMSCs. (A) Immunofluorescence staining showed that MAP-2 was barely detected in hMSCs before neurogenic induction; after the induction for 3 and 7 days, the proportions of MAP-2-positive cells increased evidently, particularly in spheroid hMSCs. (B, C) In vivo, significantly higher percentages of MAP-2-positive hMSCs in spheroid hMSCs compared with monolayer hMSCs in the ischemic lesion 7 days post-transplantation [(B, C), n=5, **P<0.01]. Color images available online at www.liebertpub.com/scd