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. 2014 Mar 4;25(4):375–384. doi: 10.1089/hum.2013.214

FIG. 3.

FIG. 3.

In vivo assessment of uterine blood flow. Serial measurements of UBF were recorded between 92±0.2 and 130±0.2 days of gestation using an ultrasonic perivascular flow probe placed around the main trunk of the UtA supplying the gravid horn in singleton-bearing adolescent ewes fed a control (C; open squares, n=12) or a high (H) dietary intake to generate normal and compromised fetal and placental growth trajectories, respectively. UBF determinations were commenced 3 days after bilateral UtA injections of Ad.VEGF (closed circles, n=18), Ad.LacZ (open triangles, n=14), or saline (open diamonds for H+Saline, n=13, and open squares for C+Saline, n=12). Asterisks denote gestational time points at which there were significant differences between the four groups (overall ANOVA p<0.05). UBF, uterine blood flow; UtA, uterine artery.