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. 2014 Mar 4;25(4):375–384. doi: 10.1089/hum.2013.214

FIG. 4.

FIG. 4.

Uterine artery vascular reactivity. Dose–response curves to phenylephrine (A) and bradykinin (B), reflecting vascular contraction and relaxation, respectively, for UtA segments (from gravid and nongravid horns at two levels of branching) from 22 singleton-bearing adolescent ewes fed a control (C; open squares) or a high (H) dietary intake to generate normal and compromised fetoplacental growth, respectively, and necropsied at 131±0.2 days of gestation. At 89±0.2 days of gestation, H ewes received bilateral uterine artery injections of Ad.VEGF (closed circles) or Ad.LacZ/Saline (open circles). Asterisks indicate concentrations of bradykinin at which there were significant differences in H+Ad.VEGF versus H+Ad.LacZ/Saline and C+Saline groups (p<0.05 for overall ANOVA and post hoc comparisons).