Table 1.
Pt # | Gender | Histology | Metastatic disease site | Vax # | Clinical response before immunotherapy | Clinical response after immunotherapy | Additional treatment before immunotherapy | Adverse effects (grade) | Survival in months |
---|---|---|---|---|---|---|---|---|---|
01 |
F |
CC |
Liver |
1 |
PD |
PD |
Sunitinib |
No |
20 m+ |
02 |
M |
CC |
Lung, bone |
1 |
PD |
PD |
None |
No |
20 m+ |
03 |
M |
CC |
Lung, bone |
1 |
PD |
PR |
None |
No |
20 m+ |
04 |
M |
CC |
Lung, bone |
2 |
PD |
SD |
None |
No |
19 m+ |
05 |
M |
CC |
Lung, Liver |
6 |
SD |
PR |
None |
No |
19 m+ |
06 |
M |
CC |
Bone |
4 |
PD |
SD |
None |
No |
18 m+ |
07 |
M |
CC |
Bone |
1 |
PD |
SD |
None |
No |
17 m+ |
08 |
M |
CC |
Lung |
4 |
SD |
PR |
None |
No |
18 m+ |
09 |
M |
CC |
Lung, Liver, Brain |
2 |
PD |
SD |
None |
No |
21 m+ |
10 |
M |
CC |
Chest |
3 |
PD |
SD |
None |
No |
16 m+ |
11 |
M |
CC |
Lung |
1 |
PD |
PR |
None |
No |
16 m+ |
12 |
M |
CC |
Liver |
1 |
PD |
PD |
None |
Fever (grade1) |
15 m+ |
13 |
M |
CC |
Neck lymph |
1 |
PD |
CR |
None |
No |
10 m+ |
14 |
M |
CC |
Lung |
1 |
PD |
SD |
None |
No |
10 m+ |
15 |
M |
CC |
Lung |
3 |
PD |
PR |
None |
No |
9 m+ |
16 |
M |
CC |
Lung |
3 |
PD |
CR |
None |
No |
10 m+ |
17 |
M |
CC |
Abdominal |
1 |
PD |
CR |
None |
No |
15 m+ |
18 |
M |
CC |
Lung |
1 |
PD |
PD |
None |
No |
12 m+ |
19 |
M |
CC |
peritoneum lymph |
1 |
SD |
PR |
None |
No |
21 m+ |
20 |
F |
CC |
Liver, Bone |
1 |
PD |
PD |
None |
No |
15 m+ |
21 |
F |
CC |
Abdominal |
2 |
PD |
PD |
None |
No |
16 m+ |
22 |
M |
CC |
Bone |
2 |
SD |
CR |
sorafenib |
No |
20 m+ |
23 |
M |
CC |
Lung, Bone |
3 |
SD |
SD |
None |
No |
6 m+ |
24 |
F |
CC |
Lung, Bone |
1 |
PD |
death |
None |
No |
4 m+ |
25 |
M |
CC |
Lung, Liver |
3 |
PD |
PR |
Sorafenib + Sunitinib |
No |
6 m+ |
26 |
F |
CC |
Peritoneum lymph |
2 |
SD |
SD |
None |
No |
11 m+ |
27 |
M |
CC |
Lung, Bone |
2 |
PD |
SD |
None |
No |
5 m+ |
28 | M | CC | Lung | 2 | SD | SD | sorafenib | No | 5 m+ |
Abbreviations: PT patient, VAX vaccination, M male, CC renal clear cell carcinoma, F female, SD stable disease, CR completed response, PR partial response, PD progression of disease.