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. 2014 Apr 11;171(9):2291–2299. doi: 10.1111/bph.12581

Figure 3.

Figure 3

Cysteine thiols are involved in H2O2 modulation of responses mediated by GABAAρ1 receptors. Potentiation of GABAAρ1 receptors responses (0.3 μM GABA) by H2O2 (500 μM) was (A) enhanced when cysteine thiols were reduced with DTT (2 mM); *P < 0.03, n = 6 and (B) prevented when sulfhydryl residues were alkylated by NEM (30 μM); ***P < 0.0001, n = 8.