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Hydroxyl radicals are involved in H2O2 potentiation of GABAAρ1 receptors responses. Potentiation of GABAAρ1 receptor responses by H2O2 (500 μM) was decreased in the presence of (A) the free radical scavenger LA (200 μM); **P < 0.001, n = 6 or (B) the iron chelator deferoxamine (100 μM); **P < 0.002, n = 6 and was enhanced (C) after pre-incubation with FeSO4 (100 μM); **P < 0.005, n = 6.
