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. 2014 Apr 23;9(4):e90163. doi: 10.1371/journal.pone.0090163

Table 3. Association of ThinPrep Bronchial Brushing Cytology with Lung Cancer Histology.

Histological Diagnosis (No. of Cases)
Positive Negative Total SEN (%) SPE (%) PPV (%) NPV (%) MCC
LC Positive 417 43 460 87.05 62.93 90.65 54.07 0.473
Negative 62 73 135
Total 479 116 595
SSC Positive 195 37 232 87.44 90.05 84.05 92.29 0.820
Negative 28 335 363
Total 223 372 595
ADC Positive 47 47 94 61.04 90.93 50.00 94.01 0.464
Negative 30 471 501
Total 77 518 595
SCLC Positive 94 14 108 61.84 96.84 87.04 88.09 0.664
Negative 58 429 487
Total 152 443 595

Note: LC, lung cancer; SCC, squamous cell carcinoma; ADC, adenocarcinoma; SCLC, small cell lung carcinoma; SEN, sensitivity; SPE, specificity; PPV, positive predictive value; NPV, negative predictive value; MCC, Matthews correlation coefficient.