Figure 8. Ingenuity Pathways analysis of lens proteins identified in αA-R49C knock-in mutant lenses.
Analysis of altered protein networks by Ingenuity Pathway software. Biological networks and pathways generated from input data (Wild-type vs. αA-R49C, Tables 1-3 and Table S1) indicate proteins with altered abundance in gray. (A) A network with HSPA8 at the hub. (B) A second network highlights Histone H4 at the hub of the protein connectivity map. Additional networks are shown in Fig. S3 in File S1.