Table 4. Quantitative analysis of protein abundance in 14-day-old WT, αB-R120G lenses heterozygous and homozygous.
| Spot number | Protein | UNIPROT accession number | MW (kDa) | Number of assigned spectra | WT1 vs. WT2 | WT1 vs. heterozygous | WT2 vs. heterozygous |
| 2982 | αB-crystallin | P23927 | 20 | 2 | 1.19 | −1.82 | −2.34 |
| αA-crystallin | Q569M7 | 20 | 1 | ||||
| RIKEN cDNA 2210010C04, isoform CRA_b | Q9CPN9 | 26 | 1 | ||||
| Probable peptide chain release factor C12orf65 homolog, mitochondrial | Q80VP5 | 21 | 1 | ||||
| 4441 | αA-crystallin | Q569M7 | 20 | 1 | 1.13 | −2.03 | −2.48 |
| 5353 | Phosphoglycerate mutase | O70250 | 29 | 2 | 1.15 | −2.06 | −2.55 |
| 5432 | βB1-crystallin | Q9WVJ5 | 28 | 17 | 1.06 | −1.81 | −2.06 |
| βB3-crystallin | Q9JJU9 | 24 | 5 | ||||
| αA-crystallin | Q569M7 | 20 | 1 | ||||
| αB-crystallin | P23927 | 20 | 1 | ||||
| 5441 | βB1-crystallin | Q9WVJ5 | 28 | 2 | 1.06 | −1.93 | −2.2 |
| Phosphoglycerate mutase | O70250 | 29 | 2 | ||||
| 5456 | βB1-crystallin | Q9WVJ5 | 28 | 5 | 1.22 | −1.94 | −2.56 |
| Phosphoglycerate mutase | O70250 | 29 | 4 | ||||
| γC-crystallin | Q61597 | 21 | 1 | ||||
| γB-crystallin | Q6PHP7 | 21 | 1 | ||||
| 5468 | Phosphoglycerate mutase | O70250 | 29 | 2 | −1.03 | −2.4 | −2.52 |
| 5492 | βB1-crystallin | Q9WVJ5 | 28 | 1 | 1.17 | −2.95 | −3.72 |
| Riken cDNA2210010C04 isoformCRA-b | Q9CPN9 | 26 | 1 | ||||
| 5960 | Putative uncharacterized protein | Q8C2C1 | 20 | 1 | 1.3 | −2.52 | −3.52 |
| γB-crystallin | Q6PHP7 | 21 | 1 | ||||
| Riken cDNA2210010C04 isoformCRA-b | Q9CPN9 | 26 | 1 | ||||
| 6005 | γC-crystallin | Q61597 | 21 | 1 | 1.54 | −1.81 | −2.99 |
| 6056 | αB-crystallin | P23927 | 20 | 25 | −1.17 | 9.23 | 10.02 |
| βB2-crystallin | P62696 | 23 | 10 | ||||
| βA3/A1-crystallin | Q9QXC6 | 25 | 9 | ||||
| αA-crystallin | Q569M7 | 20 | 7 | ||||
| βS-crystallin | O35486 | 21 | 4 | ||||
| γD-crystallin | Q6PGI0 | 21 | 4 | ||||
| βB3-crystallin | Q9JJU9 | 24 | 4 | ||||
| γB-crystallin | Q6PHP7 | 21 | 2 | ||||
| βA2-crystallin | Q9JJV1 | 22 | 2 | ||||
| 6415 | αA-crystallin | Q569M7 | 20 | 7 | 3.28 | 10.01 | 2.83 |
| 6449 | αA-crystallin | Q569M7 | 20 | 53 | 2 | 12.67 | 5.87 |
| 6848 | Grifin | Q9D1U0 | 16 | 5 | −1.04 | 2.42 | 2.33 |
| αA-crystallin | Q569M7 | 20 | 5 | ||||
| 6920 | αA-crystallin | Q569M7 | 20 | 4 | −1.55 | 1.89 | 2.71 |
| 7257 | αA-crystallin | Q569M7 | 20 | 6 | −1.13 | 2.7 | 2.84 |
| 7451 | αB-crystallin | P23927 | 20 | 6 | 1.13 | 5.61 | 4.59 |
| αA-crystallin | Q569M7 | 20 | 5 | ||||
| βB3-crystallin | Q9JJU9 | 24 | 2 | ||||
| 7739 | αA-crystallin | Q569M7 | 20 | 5 | −1.11 | 2.39 | 2.47 |
| Riken cDNA2210010C04 isoform CRA-b | Q9CPN9 | 26 | 1 | ||||
| 6061 | γC-crystallin | Q61597 | 21 | 2 | −1.04 | −2.63 | −2.73 |
| αA-crystallin | Q569M7 | 20 | 2 | ||||
| γB-crystallin | Q6PHP7 | 21 | 2 | ||||
| γD-crystallin | Q6PGI0 | 21 | 1 | ||||
| γA-crystallin | P04345 | 21 | 1 |
WT, wild-type.