Table 2. Mutations (including Missense point mutations/deletion/insertion) frequencies in 45 genes (737 loci) in lung adenocarcinoma (AC), lung large cell carcinoma, lung squamous cell carcinoma and other two lung cancer samples (lung neuroendocrine carcinoma and unknown lung cancer).

Genes	Number of samples with mutations in 76 samples (Mutation frequency)	Number of AC samples with mutations (Mutation frequency in 52 AC samples)	Number of SC samples with mutations (Mutation frequency in 20 SC samples)	Number of LCC samples with mutations (Mutation frequency in 2 LCC samples)	Number of other samples with mutations (Mutation frequency in 2 other samples)
ABL1	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)
AKT1	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)
ALK	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)
APC	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)
ATM	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)
BRAF	2(2.6%)	1(1.9%)	1(5.0%)	0(0.0%)	0(0.0%)
CDH1	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)
CDKN2A	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)
CSF1R	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)
CTNNB1	3(3.9%)	3(5.8%)	0(0.0%)	0(0.0%)	0(0.0%)
EGFR	32(42.1%)	30(57.7%)	1(5.0%)	0(0.0%)	1(50.0%)
ERBB2	1(1.3%)	1(1.9%)	0(0.0%)	0(0.0%)	0(0.0%)
ERBB4	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)
FBXW7	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)
FGFR1	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)
FGFR2	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)
FGFR3	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)
FLT3	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)
GNAS	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)
HNF1A	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)
HRAS	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)
IDH1	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)
JAK3	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)
KDR	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)
KIT	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)
KRAS	4(5.3%)	4(7.7%)	0(0.0%)	0(0.0%)	0(0.0%)
MET	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)
MLH1	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)
MPL	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)
NOTCH1	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)
NPM1	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)
NRAS	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)
PDGFRA	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)
PIK3CA	2(2.6%)	1(1.9%)	1(5.0%)	0(0.0%)	0(0.0%)
PTEN	1(1.3%)	1(1.9%)	0(0.0%)	0(0.0%)	0(0.0%)
PTPN11	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)
RB1	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)
RET	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)
SMAD4	1(1.3%)	1(1.9%)	0(0.0%)	0(0.0%)	0(0.0%)
SMARCB1	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)
SMO	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)
SRC	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)
STK11	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)
TP53	17(22.4%)	10(19.2%)	6(30.0%)	1(50.0%)	0(0.0%)
VHL	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)	0(0.0%)