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. 2014 Apr 23;9(4):e94768. doi: 10.1371/journal.pone.0094768

Table 2. Rate of overall survival ADCs by patients' characteristics.

Variables Categories ADCs (n = 435) P-value CERVICAL CA (n = 34) P-value KAPOSI SARCOMA (n = 184) P-value NON HODGKIN LYMPHOMA (n = 217) P-value
1y 5y 10y 1y 5y 10y 1y 5y 10y 1y 5y 10y
Total 77.0±2.0 67.7±2.4 61.1±2.9 90.9±5.0 87.3±6.0 78.5±9.9 86.9±2.5 79.1±3.2 72.8±4.0 66.6±3.2 55.0±3.5 48.2±4.3
Gender 0.613 NE* 0.498 0.874
Male 77.8±2.3 66.7±2.7 60.5±3.2 - - - 87.7±2.6 79.2±3.3 73.5±4.1 66.9±3.6 54.6±4.0 47.4±4.9
Female 76.8±4.5 71.7±4.9 63.8±6.1 90.9±5.0 87.3±6.0 78.5±9.9 76.9±11.7 76.9±11.7 65.9±14.3 65.1±7.6 57.0±8.0 51.3±9.0
Age, years 0.372 0.751 0.911 0.619
18–34 82.4±4.3 76.2±5.0 65.1±6.7 100 100 66.7±2.7 89.6±4.9 83.7±6.1 69.6±9.0 67.1±8.5 57.8±9.7 57.8±9.7
35–49 74.9±2.8 65.7±3.1 59.8±3.7 85.7±7.6 80.4±8.8 80.4±8.8 84.7±3.8 76.0±4.6 73.6±5.0 66.4±4.0 56.1±4.4 46.4±5.5
50-max 77.8±4.3 65.6±5.1 61.5±6.2 100 - - 89.0±4.6 81.5±6.0 74.1±8.9 66.7±6.8 49.7±7.6 49.7±7.6
IDVU <0.001 0.060 0.002 0.276
No 80.7±2.3 73.2±2.7 67.7±3.5 91.3±5.9 91.3±5.9 73.0±17.0 90.0±2.5 83.4±3.3 77.8±4.4 68.0±4.2 58.1±4.7 54.6±5.5
Yes 69.3±3.9 56.4±4.3 48.6±4.8 90.0±9.5 80.0±12.6 80.0±12.6 74.8±7.3 62.5±8.3 53.8±9.1 64.7±5.0 51.4±5.4 42.0±6.2
AIDS event 0.024 0.273 0.162 0.022
No 79.0±2.6 73.4±2.9 65.4±4.0 90.5±6.4 90.5±6.4 90.5±6.4 88.8±3.3 86.3±3.7 74.8±6.3 70.5±4.0 61.8±4.3 55.5±5.8
Yes 74.3±3.3 60.4±3.8 55.2±4.1 91.7±8.0 81.5±11.9 61.1±19.8 85.0±3.8 72.2±5.0 70.2±5.2 60.2±5.5 44.4±5.8 37.8±6.1
Coinfection 0.075 0.957 0.129 0.895
No 78.6±2.6 70.8±3.0 67.4±3.5 85.7±9.3 85.7±9.3 85.7±9.3 88.8±2.8 82.1±3.6 76.5±4.6 65.5±4.7 55.5±5.0 55.5±5.0
Yes 75.0±3.2 63.61±3.7 53.7±4.5 94.7±5.1 88.8±7.5 76.1±13.4 82.8±5.2 72.5±6.3 64.7±7.7 67.7±4.5 54.8±5.0 44.2±6.0
cART 0.001 0.660 0.007 0.024
No 63.7±5.5 51.7±5.9 49.6±6.0 90.0±9.5 90.0±9.5 90.0±9.5 67.4±9.5 58.9±10.0 58.9±10.0 55.5±7.7 39.2±7.8 35.9±7.8
Yes 80.0±2.2 71.3±2.5 63.6±3.2 91.3±5.9 86.5±7.3 74.1±13.0 90.0±2.4 82.4±3.2 75.0±4.3 69.4±3.5 59.3±3.9 51.7±4.9
CD4+ count, cell/mm3 <0.001 0.003 0.001 0.001
200-max 84.3±2.6 76.6±3.2 70.6±4.2 96.1±3.8 96.1±3.8 96.1±3.8 94.1±2.9 89.6±4.1 86.2±5.2 74.6±4.3 62.9±5.0 53.2±6.9
0–199 64.3±3.6 53.7±3.9 49.3±4.1 71.4±17.1 57.1±18.7 42.9±18.7 78.8±4.6 69.1±5.3 64.3±5.9 50.8±5.4 39.5±5.3 36.9±5.6
Nadir CD4+ count, cell/mm3 <0.001 0.085 0.001 0.033
≥200 87.4±3.2 81.3±3.8 77.9±4.9 100 100 100 97.9±2.1 93.0±3.9 85.9±7.8 73.3±6.3 63.9±7.1 63.9±7.1
50–199 69.3±3.5 77.7±3.1 61.4±4.4 75.0±15.3 62.5±17.1 62.5±17.1 88.8±3.7 84.0±4.5 75.6±6.1 69.8±4.6 59.2±5.1 49.9±6.6
<50 67.5±4.1 54.5±4.5 48.8±4.9 90.0±9.5 90.0±9.5 90.0±9.5 75.5±5.7 61.9±6.6 58.8±7.0 56.8±6.2 42.8±6.3 37.1±6.8
HIVRNA, copies/mL 0.020 0.841 0.015 0.032
Undetectable 84.8±3.5 77.8±4.3 72.6±5.3 91.7±7.9 91.7±7.9 61.1±25.5 97.6±2.3 91.2±5.0 86.1±6.8 73.2±6.1 64.4±6.8 64.4±6.8
Positive 70.8±2.8 60.0±3.2 54.8±3.6 90.5±6.4 84.8±8.1 84.8±8.1 80.4±3.9 71.7±4.6 67.5±5.2 60.2±4.2 47.1±4.5 40.2±5.1

Note: Plus minus are value standard error, P value are from long rank test. - The sample size was too small for Kaplan Meier analysis.

*NE, not evaluable. ADCs: AIDS-defining cancers, IVDU: Intravenous Drug Use, cART: combined antiretroviral therapy; CA: cancer.