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. 2014 Apr 23;9(4):e94768. doi: 10.1371/journal.pone.0094768

Table 3. Rate of overall survival NADCs by patients' characteristics.

Variables Categories NADCs (n = 431) P-value LIVER CA (n = 69) P-value LUNG CA (n = 35) P-value BREAST CA (n = 30) P-value HODGKIN LYMPHOMA (n = 61) P-value
1y 5y 10y 1y 5y 10y 6month 1y 3y 5y 10y 1y 5y 10y
Total 76.1±2.1 59.2±2.7 45.0±4.1 59.8±6.0 31.9±6.4 - 54.4±8.7 28.0±8.6 96.7±3.3 78.1±8.9 65.1±14.0 74.2±5.7 57.8±7.2 24.8±11.2
Gender 0.152 0.380 NE* 0.089 0.003
Male 74.7±2.4 56.8±3.1 40.9±4.8 56.0±6.5 27.4±6.8 - 58.3±9.3 32.0±9.6 80.0±17.9 53.3±24.8 26.7±22.6 77.0±5.8 63.0±7.5 27.1±12.2
Female 80.4±4.0 67.4±5.1 58.6±6.5 87.5±11.7 62.5±17.1 - - - 90.3±6.6 83.9±8.7 83.9±8.7 50.0±20.4 - -
Age, years 0.331 0.096 0.094 0.108 0.045
18–34 82.3±6.6 68.4±8.4 62.1±9.6 - - - - 66.7±2.7 33.3±2.7 33.3±2.7 83.1±11.0 71.2±14.5 71.2±14.5
35–49 76.2±2.7 58.1±3.5 42.4±5.3 67.9±6.8 33.2±7.5 - 42.8±13.2 14.3±9.3 88.2±7.9 80.9±10.1 53.9±23.0 68.3±7.6 49.5±8.6 9.9±9.0
50-max 74.2±3.8 59.4±5.0 44.5±8.1 40.9±11.1 35.1±10.9 - 81.6±5.3 71.1±6.4 - - - 88.9±10.5 88.9±10.5 88.9±10.5
IVDU 0.007 0.753 0.606 0.292 0.686
No 81.7±2.5 63.1±3.7 53.5±5.4 60.5±13.8 32.3±16.7 - 57.9±12.2 30.4±13.4 86.5±7.3 80.8±8.8 80.8±8.8 78.1±7.3 60.2±9.8 60.2±9.8
Yes 68.7±3.5 54.1±4.0 37.2±5.5 59.6±6.7 31.8±6.7 - 50.9±12.5 25.5±11.0 100 66.7±2.7 - 70.0±8.9 56.1±10.2 18.7±11.3
AIDS event 0.008 0.683 0.074 0.480 0.021
No 78.5±2.7 67.4±3.3 48.6±6.0 56.8±7.9 40.5±8.4 - 56.7±10.9 39.2±11.4 92.9±6.8 85.1±9.7 63.8±19.8 82.2±7.3 74.8±9.7 24.9±20.6
Yes 72.8±3.4 48.6±4.3 39.7±5.4 64.3±9.1 22.7±9.3 - 50.3±14.4 - 82.5±11.3 68.7±15.7 68.7±15.7 65.5±8.8 41.3±9.7 20.7±11.4
Coinfection 0.146 NE* 0.295 0.850 0.699
No 78.1±3.1 62.2±4.1 52.1±6.1 - - 63.6±11.1 33.9±12.6 83.5±10.8 74.3±13.0 74.3±13.0 64.5±9.1 59.6±9.7 59.6±9.7
Yes 74.5±2.9 56.9±3.6 40.6±5.2 59.8±6.0 31.9±6.4 42.9±13.2 21.4±11.0 92.9±6.9 79.6±13.6 39.8±28.9 83.3±6.8 59.0±9.9 19.7±11.8
cART 0.152 0.572 NE* NE* 0.532
No 71.9±6.4 47.2±7.4 43.9±7.6 57.1±16.4 45.7±16.6 - - - - - - 80.0±17.9 40.0±21.9 -
Yes 76.7±2.2 61.0±2.9 45.1±4.5 60.2±6.5 29.0±7.0 - 57.0±9.4 34.1±9.9 96.7±3.3 78.1±8.9 65.1±14.0 73.7±6.1 60.4±7.5 25.9±11.7
CD4+ T-cell count, cell/mm3 0.014 0.225 NE* 0.270 0.006
200-max 78.1±2.4 62.4±3.2 48.7±5.1 61.6±6.9 38.8±8.2 - 61.7±9.6 32.1±10.4 91.7±8.0 81.5±11.9 81.5±11.9 83.2±5.8 63.3±8.6 25.3±14.3
0–199 68.7±4.7 48.8±5.3 32.7±7.0 59.2±11.9 17.8±9.3 - - - 80.0±12.6 68.6±15.1 51.4±18.7 50.0±13.4 40.0±13.4 -
Nadir CD4+ counts, cell/mm3 0.337 0.891 0.427 0.433 0.083
≥200 76.2±3.3 62.9±4.3 51.6±6.8 53.1±9.9 31.9±12.1 - 64.0±10.9 33.9±11.5 90.9±8.7 90.9±8.7 90.9±8.7 81.9±9.5 51.6±14.0 -
50–199 78.4±3.2 57.9±4.3 42.9±6.0 61.0±8.5 30.5±8.3 - 57.1±16.4 21.4±17.5 85.7±13.2 64.3±2.1 64.3±2.1 78.6±7.7 50.6±8.4 40.7±16.0
<50 71.1±5.0 54.4±6.2 39.5±8.8 75.0±15.3 37.5±17.1 - - - 87.5±11.7 72.9±16.5 48.6±22.7 52.7±14.1 44.0±14.3 -
HIVRNA, copies/mL 0.110 0.149 NE* 0.668 0.233
Undetectable 79.8±2.9 60.0±4.6 48.5±7.6 69.9±7.6 35.9±9.9 - 72.3±10.6 47.9±13.7 100 53.3±24.8 - 85.0±7.9 67.7±13.2 -
Positive 71.7±3.2 55.8±3.7 41.7±4.9 49.0±9.3 26.4±8.4 - - - 81.7±9.6 81.7±9.6 81.7±9.6 68.7±7.9 55.1±8.8 22.0±12.6

Note: Plus minus are value standard error, P value are from long rank test. - The sample size was too small for Kaplan Meier analysis.

*NE, not evaluable.

NADCs: Non-AIDS-defining cancers, IVDU: Intravenous Drug Use, cART: combined antiretroviral therapy; CA: cancer.