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. 2014 Apr 23;9(4):e95723. doi: 10.1371/journal.pone.0095723

Figure 7. Transduction of EphA2-positive tumor xenografts in vivo.

Figure 7

(A,B) 2×1010 vp of genomically fiber-modified, EphA2-targeted Luc/GFP reporter and control viruses were injected intratumorally into NOD-SCID mice carrying tumor xenografts (n = 6 to 9 tumors per group). Luciferase reporter gene expression in tumors was quantified 3 days after virus injection. Columns and error bars show mean values and standard deviations, respectively. RLU, relative luminescence units. * p<0.05 versus 5T/41sSK, #p<0.05 and ###p<0.001 versus 5KO1.