Table 3. Univariate and multivariate analyses of predictors of survival for the HCC patients with extrahepatic metastasis.

Variables	Hazard Ratio	95% CI	P value
Univariate analysis
Sex (Male vs. Female)	1.137	0.630∼2.053	0.669
Age (≤48 vs. >48 years)	1.098	0.681∼1.772	0.701
PS(0∼1 vs. 2∼4)	1.876	0.793∼2.638	0.132
Serum albumin (≤35 vs. >35 g/L)	0.745	0.539∼1.563	0.401
Total bilirubin(≤21 vs. >21 µmol/L)	1.683	0.997∼2.843	0.051
Prothrombin time (≤12.8 vs. >12.8 s)	1.659	1.026∼2.682	0.039
AFP level (≤400 vs. >400 ng/mL)	1.047	0.620∼1.767	0.864
Child–Pugh grade(A vs. B,C)	2.019	1.165∼3.498	0.012
Portal/hepatic vein invasion(Yes vs. No)	1.724	1.016∼2.437	0.042
CLIP Score(0∼3 vs. 4∼6)	1.129	0.768∼2.139	0.568
Site (lymph node vs. others)*	1.671	1.018∼2.703	0.036
Site (bone vs. others)*	0.894	0.507∼1.575	0.697
Site (lung vs. others)*	1.001	0.563∼1.779	0.998
Multivariate analysis
Site (lymph node vs. others)*	1.878	1.025∼3.161	0.040

*Site: site of extrahepatic metastases.