Table 5. The Performance of SVM Models on validation dataset with experimentally derived binding affinity from EhCaBPs (D7).

Features	SN	SP	ACC	MCC
AC&CC	83.33	60	72.73	0.45
AC&HC	100	80	90.91	0.83
AC&HC&HYC	83.33	80	81.82	0.63
AC&HYC&CC	83.33	60	72.73	0.45
AC&HYC	66.67	60	63.64	0.27

The Performance of SVM Models on validation dataset with experimentally derived binding affinity from EhCaBPs (D7)with different learning parameters on various hybrid models [γ (g) (in RBF kernel), c: parameter for trade-off between training error & margin] where SN–sensitivity, SP–specificity, ACC-accuracy, MCC–Matthews Correlation Coefficient, AUC/ROC-Area under curve/ Receiver Operating Curve.