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. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: Neurogastroenterol Motil. 2014 Mar 4;26(5):715–730. doi: 10.1111/nmo.12326

Figure 2.

Figure 2

BDNF is preferentially upregulated in LS spinal cord of female CPS+HeICS rats. A. Western blots show BDNF expression in LS spinal cord dorsal horns from female and male Ctr. and CPS rats at baseline, n=6. B. Western blots show BDNF expression in LS spinal cord dorsal horns from female and male control (Ctr.) and CPS rats, 24 hours after adult HeICS (*p<0.05). (2 way ANOVA: prenatal, F1,24=9.27, p=0.006, sex, , F1,24=0.61, p=0.44, interaction, F1,24=3.36, p=0.079, CPS F vs. Ctr. F p=0.002, vs. Ctr. M p=0.006, vs. CPS M p=0.047. n=6) C. Western blots show BDNF expression in LS spinal cord dorsal horns from female sham stressed and stressed Ctr. and CPS rats 24 hours after adult HeICS (*p<0.05). (2 way ANOVA: prenatal, F1,24=10.7, p=0.003, adult stress, F1,24=32.7, p<0.001, interaction, F1,24=.25, p=0.62, within HeICS, CPS F vs. Ctr. F p=0.014, within CPS F, stress vs. sham, p<0.001, within Ctr. F, stress vs. sham, p=0.001, n=6). D. Western blots show BDNF expression in LS spinal cord dorsal horns from female sham stressed and 2× HeICS stressed CPS rats 2 weeks after adult HeICS (*p<0.05, n=6). E. Western blots show BDNF expression in LS spinal cord dorsal horns from male sham stressed and 2× HeICS stressed CPS rats 2 weeks after adult HeICS, n=6.