Table 1.

Effect of nutrient restriction in T. cruzi

Nutrient restriction	Effect	Reference
Starvation	Apoptosis-like cell death	[109]
	Autophagy and differentiation	[53]
	eIF2-α phosphorylation, translation repression, differentiation	[49]
	Metacyclogenesis	[48, 47]
	Decrease in ATP, reduced infectivity	[110]
Delipidated serum	Cholesterol mobilization from reservosomes	[46]
Polyamines	Growth inhibition, increased uptake, translocation to membrane	[111]
Inorganic phosphate	Growth inhibition	[112]
Amino acids
Aspartate*	Increased uptake	[113]
Arginine**	Increased uptake	[114]
Cysteine	Increased uptake	[115]
Lysine	Increased uptake	[116]

^*Necessary for in vitro metacyclogenesis

^**High-affinity transporter