Table 2.
Relationship between grey matter volumes and Hamilton Depression Rating Scale (Ham-D) in late-life depression patients treated with citalopram
| LEFT | Brain Region | RIGHT | ||||||
|---|---|---|---|---|---|---|---|---|
| X (mm) | Y (mm) |
Z (mm) | Z-Score | X (mm) |
Y (mm) |
Z (mm) |
Z-Score | |
| Decrease in Ham-D score with treatment associated with smaller grey matter volumes (p < 0.01) | ||||||||
| Caudate | 9 | 11 | 14 | 2.15 | ||||
| Decrease in Ham-D score with treatment associated with larger grey matter volumes (p < 0.01) | ||||||||
| −2 | −28 | 41 | 3.05 | Cingulate Gyrus (BA 31) | 6 | −30 | 37 | 3.04 |
| −32 | 42 | 31 | 3.24 | Superior Frontal Gyrus (BA 9/8) | 15 | 42 | 44 | 3.62 |
| Middle Frontal Gyrus (BA 6) | 38 | −3 | 47 | 3.13 | ||||
| Middle Frontal Gyrus (BA 46) | 43 | 36 | 17 | 3.27 | ||||
| −29 | 43 | 19 | 3 | Middle Frontal Gyrus (BA 10) | ||||
| −56 | −17 | −4 | 3.04 | Middle Temporal Gyrus (BA 21) | 55 | −26 | −12 | 3.23 |
| Precuneus (BA 7) | 1 | −37 | 44 | 3.7 | ||||