DA tissue content decreased on average 75% following 6-OHDA lesion in striatum (n=11, *p<0.0001, t=8.58, df=10) and 40% in SN (n=11, *p=0.0016, t=4.29, df=10). The degree of tissue DA loss between these two regions following 6-OHDA differed significantly (n=11, **p=0.0044, t=3.67, df=10). B. Remaining DA in the striatum versus the SN differed significantly, being 2.4-fold greater in the SN (60%) compared to striatum (25%) against corresponding contralateral tissues.