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. Author manuscript; available in PMC: 2015 May 1.

Published in final edited form as: J Neurochem. 2014 Jan 27;129(3):548–558. doi: 10.1111/jnc.12652

Striatal tissue from control (◆) and 6-OHDA lesioned mfb (X) sides was used to compare DA tissue content (normalized to inherent TH protein to eliminate the influence of TH protein to inherent DA tissue content) with associated TH phosphorylation stoichiometries. A. ser31 to striatal DA tissue content. There was a significant correlation of TH-normalized DA tissue content with ser31 (n=14, ***p<0.0001, Pearson r=0.878). B. ser40 to striatal DA tissue content. There was a significant correlation of TH-normalized DA tissue content with ser40 (n=14, ***p<0.0001, Pearson r=0.917) C. ser31 phosphorylation to nigral DA tissue content. There was a significant correlation of TH-normalized DA tissue content with ser31 (n=14, ***p=0.0001, Pearson r=0.853). ser40 to nigral DA tissue content. No significant correlation of TH-normalized DA tissue content existed in the SN with ser40 (n=14, p=0.617, Pearson r= −0.147). As noted in the text, no relationship of striatal or nigral DA tissue content existed with ser19 phosphorylation stoichiometries determined in the lesioned and control tissues.

Striatal tissue from control (◆) and 6-OHDA lesioned mfb (X) sides was used to compare DA tissue content (normalized to inherent TH protein to eliminate the influence of TH protein to inherent DA tissue content) with associated TH phosphorylation stoichiometries. A. ser31 to striatal DA tissue content. There was a significant correlation of TH-normalized DA tissue content with ser31 (n=14, ***p<0.0001, Pearson r=0.878). B. ser40 to striatal DA tissue content. There was a significant correlation of TH-normalized DA tissue content with ser40 (n=14, ***p<0.0001, Pearson r=0.917) C. ser31 phosphorylation to nigral DA tissue content. There was a significant correlation of TH-normalized DA tissue content with ser31 (n=14, ***p=0.0001, Pearson r=0.853). ser40 to nigral DA tissue content. No significant correlation of TH-normalized DA tissue content existed in the SN with ser40 (n=14, p=0.617, Pearson r= −0.147). As noted in the text, no relationship of striatal or nigral DA tissue content existed with ser19 phosphorylation stoichiometries determined in the lesioned and control tissues.