Table I.
Differences between the intracellular localization of survivin in the normal mucosa, HSIL and SCC (%).
| Localization | Normal mucosa, n (%) | HSIL, n (%) | SCC, n (%) | Total, n (%) | P-value |
|---|---|---|---|---|---|
| Nucleus | 15 (100) | 7 (28.0) | 14 (45.2) | 36 (50.7) | |
| Cytoplasm | 0 (0) | 18 (72.0) | 17 (54.8) | 35 (49.3) | |
| Duala | 0 (0) | 16 (64.0) | 13 (41.9) | 29 (40.8) | <0.001b |
| Total | 15 (21.1) | 25 (35.2) | 31 (43.7) | 71 (100.0) |
a
Localization to the nucleus and cytoplasm;
b
P<0.05 was considered to indicate a stastically significant difference.
HSIL, high-grade squamous intraepithelial lesion; SCC, squamous cell carcinoma.