Table 2.

Summary of modelling and validation datasets

Dataset	No. of patients	No. of FIX activity records	Age (years) [median (range)]	Body weight (kg) [median (range)]
Modelling dataset	12 (phase 1/2a) 123 (phase 3)	1,400	31.3 (12.1–76.8)	73.3 (45.0–186.7)
Validation dataset	100 (phase 3)a	1,027	30.7 (12.1–71.6)	72.5 (45.2–186.7)

FIX factor IX

^aPhase 1/2a was a single-dose study; no peaks/troughs were collected