Table 2.
Endometrioid carcinoma of the endometrium with signet-ring cells: immunohistochemical results in two tumoral components of our case.
| Immunostaining | Endometrioid adenocarcinoma | Signet-ring cell carcinoma |
|---|---|---|
| CD56 | Negative | Negative |
| Synaptophysin | Negative | Negative |
| CEA | Negative | Negative |
| Ki-67 | 5% | <2% |
| Chromogranin A | Negative | Negative |
| E-cadherin | Positive | Positive |
| HER-2 | Negative | Negative |
| Estrogen receptor | Focally positive | Negative |
| Progesterone receptor | Weak positivity | Negative |
| Vimentin | Positive | Positive |
| p16 | Positive | Positive |