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. 2014 Apr 3;2014:502872. doi: 10.1155/2014/502872

Table 3.

Effect of repeated oral administration of 25 mg/kg BW of tilmicosin daily for 5 consecutive days on some biochemical parameters in broiler chicken (n = 5).

Parameters Days
Control 1 5 10 15 20
Creatinine (mg/dL) 1.67 ± 0.20 1.79 ± 0.03 1.81 ± 0.07 1.90 ± 0.07 1.88 ± 0.05 1.92 ± 0.06
Uric acid (mg/dL) 5.31 ± 0.17 5.89 ± 0.23 5.94 ± 0.39 5.90 ± 0.12 5.78 ± 0.06 5.78 ± 0.08
Sodium (mmol/L) 115.6 ± 10.85ab 94.6 ± 0.92c 100.6 ± 2.56bc 105.8 ± 1.07abc 110 ± 3.36abc 118.4 ± 4.01a
Potassium (mmol/L) 5.15 ± 0.14c 5.45 ± 0.13abc 5.32 ± 0.20bc 5.68 ± 0.06ab 5.77 ± 0.06ab 5.81 ± 0.13a
Calcium (mg/dL) 9.44 ± 0.14ab 9.59 ± 0.13a 9.75 ± 0.11a 9.97 ± 0.24a 9.88 ± 0.09a 9.01 ± 0.20b
Glucose (mg/dL) 111.41 ± 2.61ab 118.91 ± 3.96a 120.63 ± 5.57a 122.39 ± 3.43a 107.63 ± 2.86b 117.70 ± 1.24ab
T. protein (g/dL) 4.80 ± 0.32a 3.57 ± 0.15b 3.46 ± 0.12b 3.87 ± 0.11b 4.51 ± 0.16a 4.68 ± 0.07a
Albumin (g/dL) 2.26 ± 0.09a 1.50 ± 0.07b 1.18 ± 0.03c 1.25 ± 0.06c 2.24 ± 0.06a 2.22 ± 0.07a
AST (U/L) 176.53 ± 3.91b 185.54 ± 4.62ab 186.1 ± 3.10ab 176.49 ± 1.66b 188.56 ± 7.06ab 197.99 ± 1.29a
ALT (U/L) 53.67 ± 0.36a 53.45 ± 1.09a 51.13 ± 0.36b 51.28 ± 0.53b 50.60 ± 0.38b 52.15 ± 0.69ab
ALP (U/L) 381.51 ± 8.70 365.99 ± 15.72 382.30 ± 6.34 378.01 ± 13.46 373.16 ± 11.67 391.50 ± 4.84
Cholesterol (mg/dL) 191.30 ± 4.23cd 184.25 ± 5.18d 206.58 ± 4.69b 201.13 ± 5.15bc 195.63 ± 3.62bc 221.65 ± 4.27a
Triglycerides (mg/dL) 186.48 ± 3.31c 181.95 ± 5.76c 204.40 ± 5.98b 219.98 ± 3.93a 223.73 ± 3.91a 224.29 ± 5.38a
HDL-chol (mg/dL) 150.2 ± 1.62ab 141.9 ± 3.18b 151.6 ± 3.65a 142.42 ± 3.98b 147.8 ± 1.83ab 150.68 ± 1.11ab

a,  b,  c,  dMean values having different letters in column differ significantly (P < 0.05).