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. 2014 Apr 24;4:4775. doi: 10.1038/srep04775

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(a) RMSD of MMP-2 fluctuates between 1 and 3 Å for both Gd@C₈₂(OH)₂₂ (up) and C₈₂(OH)₂₂ (down), where each trajectories are represented with different colors. (b) RMSF of MMP-2 with Gd@C₈₂(OH)₂₂ (up) and C₈₂(OH)₂₂ (down). Five β-sheets and three α-helices seem stable, while loops from both upper and lower rims are more sensitive to fullerene derivatives.