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. 2014 Apr 16;45(1):45. doi: 10.1186/1297-9716-45-45

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Copyright © 2014 Anand et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Electron microscopy of BAdV-3 infected cells. (A) MDBK cells mock infected (panel a, b) or infected with wild-type BAdV-3 (panels c, d, e, f) at a MOI of 5 were analyzed after 6 (panel c, d) and 12 (panel e, f) hpi. Figures in the left panels (panels a, c, e) show the cytoplasm in the vicinity of the mitochondria. Area covered by white rectangles is enlarged and shown in the panels (panel b, d, f) on the right. Protein factories (PF) in the vicinity of the damaged mitochondria at 6 (panel d) and 12 (panel f) hpi. Bar = 0.25 μ. (B) MDBK cells infected with wild-type BAdV-3 at an MOI of 5 were analyzed at 24 hpi. An infected cell showing the virus particles (V) in the nucleus and the damaged mitochondria (M) in the cytoplasm (panel a). The enlarged area indicated by a rectangle (M) in panel “a” showing the mitochondria with amorphous internal structure in the cytoplasm of the infected cell (panel b). The enlarged area indicated by a rectangle (V) in panel “a” showing virus particles (indicated by arrows) in the nucleus of infected cells (panel c). Bar = 0.25 μ.