Fasting for at least 4–6 hours

Oral hydration with water should be encouraged

Avoid caffeine, alcohol, or drugs that may affect cerebral glucose metabolism

Check blood glucose level (ideally not greater than 150–200 mg/dL)

Environmental conditions: “resting state”, patient with eyes open and ears unoccluded in a quiet, dimly-lit room, with minimal background noise

Start intravenous line for 18F-FDG administration (at least 10 minutes prior to tracer injection)