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. Author manuscript; available in PMC: 2015 Mar 6.
Published in final edited form as: Cell Stem Cell. 2014 Mar 6;14(3):306–321. doi: 10.1016/j.stem.2014.02.002

Figure 5. Three possible sources of metastatic niche support.

Figure 5

Disseminated cancer cells can obtain stem cell niche support by occupying native stem cell niches including perivascular sites, by recruiting stromal cells that produce stem cell niche-like components, or by producing niche components themselves.