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. 2014 Jan 7;86(4):1972–1979. doi: 10.1021/ac403901t

Table 2. Centroid Distance from Origin and RMS Spread Values of Protein Analysis and Quantitation Methodsa.

method centroid distance from origin RMS spread
LC-IM-DIA-MS 1.12 0.10
LC-DIA-MS 1.73 0.30
LC-IM-DIA-MS2-High3 1.74 0.16
a

Similar centroid distance values indicate quantitative agreement between methods across the range of protein abundance. Lower RMS spread values indicate a greater signal to noise ratio.