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. Author manuscript; available in PMC: 2014 Apr 24.
Published in final edited form as: J Health Soc Behav. 2013 May 6;54(2):183–203. doi: 10.1177/0022146513485244

Table 4.

Social Isolation, Inflammation, and Mortality: Model 1 HRs Adjusted for Age and Race and Model 2 HRs Adjusted for All Covariates.

Men Women


All Ages 40–64 Years ≥65 Years All Ages 40–64 Years ≥65 Years

Model 1 Model 2 Model 1 Model 2 Model 1 Model 2 Model 1 Model 2 Model 1 Model 2 Model 1 Model 2
All-cause mortality
  Social isolation 1.69*** 1.45*** 1.47* 1.16 1.88*** 1.67*** 1.82*** 1.46*** 1.62* 1.24 1.90*** 1.57***
  Inflammation index (0) 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00
    1 1.65*** 1.56*** 1.74** 1.57* 1.57*** 1.50*** 1.34** 1.30** 1.59* 1.17 1.25** 1.25*
    2 or 3 3.03*** 2.60*** 5.12*** 3.82*** 2.41*** 2.21*** 1.72*** 1.48** 2.61*** 1.49 1.49*** 1.40**
Circulatory disease mortality
  Social isolation 1.66*** 1.49** 1.20 1.03 1.97*** 1.87*** 1.72*** 1.47** 1.20 1.12 1.87*** 1.63**
  Inflammation index (0) 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00
    1 1.46** 1.35* 1.18 1.08 1.55** 1.46** 1.04 1.01 1.68 1.25 .94 .91
    2 or 3 2.50*** 2.05*** 4.53*** 3.04** 2.01*** 1.78** 1.50** 1.30 3.65** 2.10 1.25 1.15
Cancer mortality
  Social isolation 1.44 1.21 1.78 1.27 1.19 1.10 1.07 .87 1.09 .75 1.02 .91
  Inflammation index (0) 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00
    1 2.07*** 1.99*** 1.84 1.48 2.20*** 2.14*** 1.32 1.25 1.29 .97 1.34 1.46
    2 or 3 4.44*** 3.94*** 5.79*** 3.89** 3.99*** 3.83*** 1.64* 1.36 1.66 1.00 1.63 1.69

Note: HR = hazard ratio.

*

p < .05,

**

p < .01, and

***

p < .001 (two-tailed tests).